No. Please install CAESES into the same directory like the previous Framework installation without de-installation: the licence file and user settings like additional windows, special window settings etc. will be maintained and can be reused in the new installation.
Note that you also can have several CAESES installations in parallel. This might be useful if you work on projects, that require different versions of the CAESES.
In that case, just chose a different installation directory for each installation (like Framework_2.4, Framework_3.0, ...).